The Goldilocks Effect in Prescription Drugs
Posted by Literary Titan

The Goldilocks Genome follows an epidemiologist investigating the death of her best friend, who uncovers more suspicious deaths that can be linked to the Goldilocks effect in prescription drugs. What was the inspiration for the setup of your story?
I heard an NPR interview with Irv Weissman, a leader in stem cell biology, was asked, “How does the lay public learn about science?” His answer: “Fiction.” Weissman’s insight inspired me to use my knowledge and background in pharmaceuticals, genetics, and epidemiology to craft a medical thriller to introduce the lay public to the importance of personalized medicine.
What were some themes that were important for you to explore in this book?
One of the most important themes I wanted to explore in The Goldilocks Genome was the concept of the Goldilocks effect in prescription drugs. Meaning the prescribed dose of a medication can be “too little”, “too much”, or “just right” depending on a person’s individual genetics. Today we have the tools to discover how our genes process prescription drugs and initiate a discussion with their healthcare provider or physician to get a prescription or dose that is right for them.
What is your background and experience, and how did it help you write the medical thriller, The Goldilocks Genome?
My doctoral research was in biomedical anthropology where I used epidemiology to study the natural history of infection with hepatitis B virus. My post-doctoral studies focused on human genetics. I then went on to build a career in pharmaceuticals where I was learned the basics of pharmacology. The Goldilocks Genome combines all of these skills and passions while using antidepressants as the drug of choice to showcase why personalized medicine is important and necessary.
What is the next book that you’re working on, and when can your fans expect it out?
My next book is a memoir, Mud, Microbes, and Medicine that goes into depths of solving the problem of how infants in a remote Melanesian culture become chronic carriers of hepatitis B virus. Beyond the science it is also my coming of age story set in the 1970s across Melanesia, Philadelphia, the Silicon Valley, and Basel, Switzerland. Mud, Microbes, and Medicine will be published April 21, 2026 and is available for pre-order on Amazon and other booksellers.
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To unravel the puzzle, Carrie assembles a team: some talented post-doctoral fellows, a quirky pharmacologist, an unctuous chemist, and a skeptical FBI agent that she can’t help her attraction for. Together, they follow the data through the twists and turns, eventually uncovering that the Goldilocks effect in prescription drugs—the premise that people are inclined to seek “just the right amount” of something—is central to understanding these mysterious deaths. Through the twists and turns, Carrie and her team enter a race to uncover the truth . . . and catch a killer.
Grounded in real data analysis techniques, real science and pharmacology, and actual current psychiatric practices, The Goldilocks Genome is simultaneously a taut, race-against-time thriller and a condemnation of the psychiatric industry’s failure to implement genetic-based “personalized medicine”—a problem that persists to this day.
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About Literary Titan
The Literary Titan is an organization of professional editors, writers, and professors that have a passion for the written word. We review fiction and non-fiction books in many different genres, as well as conduct author interviews, and recognize talented authors with our Literary Book Award. We are privileged to work with so many creative authors around the globe.Posted on December 16, 2025, in Interviews and tagged author, book, book recommendations, book review, Book Reviews, book shelf, bookblogger, books, books to read, ebook, Elizabeth Reed Aden, fiction, goodreads, indie author, kindle, kobo, literature, medical thriller, nook, novel, read, reader, reading, story, suspense, The Goldilocks Genome, thriller, writer, writing. Bookmark the permalink. Leave a comment.
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